This compact fluorination line is equiped with a CO₂ laser system (MIR-10, 25W) that “floats” above the sample chamber enabling the use of non-flexible tubing to the extraction line for stronger signals and lower blanks. Systems are fully controlled by computer in beam-delivery, sample-observation and sample-manipulation functions. All laser-heating (and fluorinating) operation can essentially be done with clicking of the mouse. The system can be used to extract oxygen from many non-carbonate minerals (e.g., silicate, oxides, and sulfate) for multiple oxygen isotopic analyses. A modified version (a continous-flow mode) can also be used to perform high-resolution carbon and oxygen isotopic analyses of carbonates.